You ask a very good question. I am desperately allergic to almost all animals. Cats, dogs, horses, guinea pigs etc. However I am not at all allergic to my 2 Dutch rabbits. It’s like a miracle that I can finally have a pet. I love them so much. The best thing to do is visit a shelter and play with the rabbits there. Some pet shops won’t let you pick up a rabbit until after youv have bought it and left the store. You will know pretty quickly if it bothers your allergies. IMPORTANT POINT – Just because you are not allergic to the actual rabbit, if you have hayfever or asthma the bedding might bother you. You will also have to keep your rabbit very clean and make sure they are wiped down if they have been outside running around in the weeds.